Research Projects Directory

Research Projects Directory

17,223 active projects

This information was updated 4/3/2025

The Research Projects Directory includes information about all projects that currently exist in the Researcher Workbench to help provide transparency about how the Workbench is being used. Each project specifies whether Registered Tier or Controlled Tier data are used.

Note: Researcher Workbench users provide information about their research projects independently. Views expressed in the Research Projects Directory belong to the relevant users and do not necessarily represent those of the All of Us Research Program. Information in the Research Projects Directory is also cross-posted on AllofUs.nih.gov in compliance with the 21st Century Cures Act.

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Social Support and the Hispanic Paradox

I intend to study the Hispanic paradox in survival outcomes for Hispanic patients with head and neck cancer (HNC) compared to other racial and ethnic groups. This research is important because despite facing significant socioeconomic disadvantages and barriers in healthcare…

Scientific Questions Being Studied

I intend to study the Hispanic paradox in survival outcomes for Hispanic patients with head and neck cancer (HNC) compared to other racial and ethnic groups. This research is important because despite facing significant socioeconomic disadvantages and barriers in healthcare access, Hispanic individuals paradoxically exhibit better survival rates for certain health conditions, including head and neck cancer. Limited research exists on the underlying mechanisms driving this paradox, such as social and cultural factors ("Barrio advantage"), immigration-related behaviors ("Salmon Bias," "Healthy Migrant Effect"), and lifestyle influences. Understanding these mechanisms is crucial for developing culturally tailored interventions, reducing healthcare disparities, and improving cancer care outcomes for Hispanic populations.

Project Purpose(s)

  • Population Health

Scientific Approaches

The study will utilize the All of Us Research Program database to analyze de-identified health and survey data from Hispanic and non-Hispanic individuals with Head and Neck cancer. A retrospective cohort design will be used to compare outcomes such as treatment efficacy, complication rates, and long-term health effects. Statistical analysis methods will include multivariable regression to adjust for confounding variables (e.g., age, comorbidities, cancer stage). Subgroup analyses will evaluate how factors such as implant type and radiation dose influence outcomes. Data cleaning, management, and statistical analysis will be conducted using supported tools such as R or Python

Anticipated Findings

The anticipated findings from this study include identifying whether Hispanic individuals with Head and Neck cancer experience different outcomes with social support. These differences may include variations in treatment efficacy, rates of adverse events, and long-term health outcomes. The results could provide insights into mechanisms that potentially improve cancer care outcomes for Hispanic populations.

Demographic Categories of Interest

  • Race / Ethnicity

Data Set Used

Controlled Tier

Research Team

Owner:

  • Kevin Vargas - Graduate Trainee, Baylor College of Medicine
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