FAQ Category Archives:

The Researcher Workbench’s Controlled Tier includes data from more than 447,000 participants with genotyping arrays, more than 414,000 with short-read whole genome sequences (WGS), more than 97,000 with structural variant data, and more than 2,700 with long-read WGS. To learn more about these data, please visit the Data Browser.

The All of Us Researcher Workbench uses Google sign in for all accounts.  This requires users to authenticate their account with Google and set cookies in the browser. If you are having trouble signing in, these suggestions may help: Confirm that you are using Google Chrome. Other browsers are not supported at this time. Check […]

For you to access the Registered Tier and Controlled Tier data, your institution will need to have signed a Data Use and Registration Agreement with the All of Us Research Program. If your institution is not listed, that means your institution does not have an agreement with the program yet. You can help initiate one […]

The Research Project Directory will display your name, institution, and role. This information will be displayed along with the Research Purpose Description you provided for each of your workspaces (and for your shared access workspaces). This provides All of Us participants information about who is using their data and the research the data are enabling. […]

The All of Us Research Program is committed to being transparent with its research participants about the purpose of the research that uses their data. Any participant or member of the public can request that the All of Us Resource Access Board (RAB) review a research purpose description if they have concerns that your research […]

The Resource Access Board (RAB) is charged with reviewing and auditing research projects to determine whether they may potentially stigmatize research participants or violate the Data User Code of Conduct in any other way. The RAB is composed of experts in human subjects research, research ethics, and privacy and security, as well as participant representatives.

Yes. When you create a workspace, you will be prompted to request a Resource Access Board (RAB) review of your research purpose if you are concerned about potential stigmatization of research participants. If you request a RAB review, you can expect a response within 5 business days. In the meantime, you can continue with your […]

The requester will fill out a form describing their specific concerns. This form is sent to the Resource Access Board (RAB) for review. If more information or remediation is needed, the RAB will contact the workspace owner.

The RAB will contact the workspace owner.

Yes. As a condition of your data access, you must inform the program of any upcoming publications resulting from access to All of Us Research Program data at least 2 weeks before the date of publication or presentation. This includes peer-reviewed manuscripts, conference abstracts, and/or presentations. You can do this by contacting User Support in […]

Work that uses All of Us data must honor the contribution of those who take part in All of Us to the Research Project’s work. This includes acknowledgement in all oral and written presentations, disclosures, and publications resulting from any analyses of the data. Learn more and find the citation language on the Data Access […]

The Researcher Workbench protects participant data by enabling researchers to analyze All of Us data within the Researcher Workbench without taking the participant-level data out of the secure cloud environment. You must not download, copy, or take screenshots of individual participant-level (or row-level) data and remove it from the All of Us Research Program environment.

You may upload or import external data, codes, or files into your workspace for the sole purpose of the research that you have described. You may not link Registered or Controlled Tier All of Us Research Program data at the participant level with participant-level data from other sources without the explicit, documented permission of the […]

There is no cost to access the Researcher Workbench. Computation costs for analyses, however, may be incurred through Google Cloud Platform. The All of Us Research Program provides $300 in initial credits for each registered Researcher Workbench user. These credits will help pay for preliminary storage and initial computational needs as researchers get started using […]

Analysis files are where researchers can perform comprehensive analyses on cohorts and data sets using programming languages R, Python, or SAS.

Concepts describe information in a patient’s medical record, such as a condition, a  prescription they are taking, or their vital signs. Subject areas such as conditions, drugs, measurements, etc. are called “domains”. Users can search for and save collections of concepts from a particular domain as a “concept set” and then use concept sets and cohorts […]

Datasets are analysis-ready tables that can be exported to analysis tools such as Jupyter Notebook, RStudio, and SAS Studio. Users can build and preview a dataset for one or more cohorts by selecting the desired concept sets and values for the cohorts.

The All of Us Research Program employs Observational Medical Outcomes Partnership (OMOP) Common Data Model Version 5 infrastructure to ensure feasibility and standardization across all program data types (physical measurements, electronic health records and participant provided information). Data coming from disparate sources are standardized (see What do “source” and “standard” mean? above) and stored in […]

Participants in the All of Us Research Program respond to surveys spanning a variety of topics, including demographics, health care, and lifestyle. Each survey has been tested for readability and accessibility through cognitive interviews and quantitative testing. This testing process included populations from different educational backgrounds and geographic locations to capture a sample reflective of […]

No. As noted in the All of Us Responsible Conduct of Research training, the Researcher Workbench employs a data passport model, through which authorized users do not need IRB review for each research project. Most authorized users will not be conducting human subjects research with All of Us data for two reasons:​ (1) The research will […]

You are responsible for adhering to the decisions and review processes of the All of Us IRB just as you would your own local IRB. Additionally, you must meet the requirements of your institution and must check with your local Human Research Protection Program (HRPP) regarding local submission and reporting requirements.